Looking for a Prolis alternative?
Prolis laboratory information system is cloud-based or on-premise (vendor). Here is what changes if your lab moves to SamLab, what to carry across, and when staying with Prolis is the right call.
Four questions, whichever system you run today
What happens when the connection drops
Any LIS decision starts here. SamLab keeps registration, results, reports and billing running on your own machine; Prolis states its deployment as "Cloud-based or on-premise (vendor)" — ask what its outage behaviour is for the option you are offered.
How the price is structured
Prolis: Not published — the vendor quotes after a sales conversation (checked 2026-09-03). SamLab: a yearly subscription quoted in your own currency, every plan on the public pricing page. Compare like with like over three years, not one.
Who holds the data at exit
Before you leave any system, get its export in writing. In SamLab the database is a file on your own machine, and the standard backup is a ZIP that restores without a passphrase.
Who answers when something breaks
Ask both vendors which hours support covers in your time zone and whether it is included. SamLab support is included in every plan.
The rows that move when you switch
Prolis column as published by the vendor, read on 2026-09-03. The full table is on the comparison page.
| Factor | Prolis | SamLab |
|---|---|---|
| Deployment | Cloud-based or on-premise | Offline-first desktop with cloud sync |
| Works through an internet outage | Not stated by the vendor; on-premise option exists | Yes — registration, billing, results and reports keep running |
| Pricing model | Quote-based | Yearly subscription in your own currency |
| Public, transparent pricing | Not published (directory: contact vendor) | Yes — every plan price is on the pricing page |
| Where your data lives | Vendor cloud or your own server | On your own machine first; encrypted off-site backup and export |
| Free trial on your own data | Free demo; a directory lists a free trial | 7-day free trial, no card |
Three things to do before the first live day
- 1Get an export from your current software — patients, doctors, rate list, outstanding dues — one sheet per master, and check what your contract says about your data.
- 2Pick one cut-off date the whole lab knows: bills before it stay in the old system, bills from it are in SamLab.
- 3Run the 7-day trial on your own exported data first, so the first live day is the second time you see your patients in it.
Stay with Prolis if
you bill US insurers electronically and want 837/835 EDI inside the LIS from day one.
Move to SamLab if
you are outside the US insurance system, or you want a laboratory that keeps running offline with a price you can read first.
Before you switch
Is SamLab a Prolis alternative for a small laboratory?
Prolis is a US-market LIS for CLIA-certified laboratories, from physician-office to reference and toxicology, with HL7/FHIR exchange, bidirectional analyzer connectivity and 837/835 billing built in. SamLab is an offline-first LIS with a published price sold worldwide. Prolis wins on US billing rails; SamLab wins on outage resilience, price transparency and a free trial you can run today.
Can I bring my data from Prolis laboratory information system into SamLab?
Masters — patients, doctors, rate lists, outstanding balances — come across from an export of your current system. Migration is a hands-on service with a written cut-off date, not a self-serve importer; the migration page says exactly what moves and what does not.
How does SamLab pricing differ from Prolis?
Prolis: Not published — the vendor quotes after a sales conversation (checked 2026-09-03). SamLab publishes every plan on its pricing page — a yearly subscription in your own currency — and the 7-day trial needs no card.
Sources for what we say about Prolis · read on 2026-09-03
Vendor details are taken from each vendor’s own public website on the date shown and may change. We compare on published capabilities, not on internals we cannot verify. Confirm current features and pricing directly with the vendor and in a trial. SamLab details reflect our published plans. Vendor names are used only to identify the products compared.
Try the whole lab, free for 7 days.
No card. No catch. Run SamLab on your own data — online or offline — and feel the difference before you pay anything.